Dr Emma Lane - BSc PhD
Peer reviewed articles
Kelly, C.M., Precious, S.V., Torres E.M, Harrison A., Williams, D., Scherf, C., Weyrauch, U.M, Lane E.L, Penketh, R., Kemp, P., Amso, N.N., Dunnett, S.B., Rosser, A.E. (2010)Medical terminations of pregnancy: a viable source of tissue for cell replacement therapy for neurodegenerative diseases. (Cell Transplantation, in press).
Lane E.L., Dunnett S.B. (2010) Pretreatment with dopamine agonists influences L-dopa mediated behaviours Behav. Brain Res. 213(1): 66-72.
Lane EL, Vercammen L, Cenci MA, Brundin P. (2009) Exp. Neurol. 219(1):355-8. Priming for L-dopa-induced abnormal movements increases the severity of amphetamine-induced behaviours, but different mechanisms underlie their presentation.
Lane EL, Brundin P, Cenci AM, (2009) Neurobiol. Dis. 35(1); 42-51.Amphetamine-induced abnormal movements occur independently of both transplant- and host-derived serotonin innervation following neural grafting in a model of Parkinson’s disease
Monville C, Torres EM, Pekarik V, Lane EL, Dunnett SB (2009). Brain Res Bull, 78(4-5); 248-53. Genetic, temporal and diurnal influences on L-dopa-induced dyskinesia in the 6-OHDA model.
Lane EL, Soulet D, Vercammen L, Cenci AM, Brundin P (2008), Neurobiol. Dis. 32(2): 220-8. Neuroinflammation in the generation of post-transplantation dyskinesia in Parkinson’s disease
Lane EL, Cheetham, S., Jenner P. (2008) J. Neural Trans. 115(3): 423-9. Striatal output markers do not alter in response to circling behaviour in the 6-OHDA model produced by acute or chronic administration of the monoamineuptake inhibitor BTS 74 398.
Lane EL, Winkler C, Brundin P, Cenci AM (2006) Neurobiol. Dis., 22(2): 334-45. The impact of graftsize on the development of dyskinesia after grafting ventral mesencephalic tissue in a model of Parkinson’sdisease
Lane EL, Cheetham, S., Jenner P. (2006) Exp. Neurol.. 179(2): 284-90. Does contraversive circling in the 6-OHDA model indicate an ability to induce motor complications as well as therapeutic effects in Parkinson’s disease?
Lane EL, Cheetham S., Jenner P. (2005) Eur. J. Neurosci, 21(1): 179-86. The repeated administration of the monoamine uptake inhibitor BTS 74 398 induces ipsilateral circling in the 6-hydroxydopamine model without sensitising motor behaviours.
Lane EL, Cheetham S., Jenner P. (2005) J. Pharm. Exp. Ther. 312(3): 1124-31. Dopamine uptake inhibitor induced rotation in 6-hydroxydopamine model involved both D1 and D2 receptors but is modulated through 5HT and noradrenaline receptors.
Reviews:
Lane E.L. and Smith G.A., Understanding graft-induced dyskinesia, (2010) Regen Med. 2010 Sep;5(5):787-797.
Lane E.L., Bjorklund A., Dunnett S.B., Winkler C. (2010), Progress in transplantation: Unraveling the mechanisms underlying graft-induced dyskinesia, Prog Brain Res. 2010;184:295-309
Lane EL, Handley O, Rosser A, Dunnett SB (2008) Neuropsychiatric Dis and Treatment.4(5):835-45.Potential therapies for the treatment of Parkinson’s disease
Lane EL. & Dunnett S.B. (2008) Psychopharmacology 199(3):303-12. Animal Models of Parkinson’s Disease and L-dopa induced Dyskinesia: how close are we to the clinic?
Zeitlow R, Lane EL, Dunnett SB & Rosser AE (2008) Cell and Tissue Res. 331(1): 302-22. Human stem cells for CNS repair.
Book Chapters:
Lane EL, Carlsson T., Kirik D., Dunnett SB., (2007) Animal models of Parkinson’s disease. Sourcebook of Models of Biomedical Research ch 32.pg 313-322 ed. M.Conn, Humana Press.