Welsh School of Pharmacy

Pharmacology and Physiology Research Group

Pharmacology: mechanisms of drug action, physiological regulation and disease processes

(Coordinator, Emma Kidd )

Expertise includes: elucidating mechanisms of drug action at all levels of organisation, from intracellular sites, membranes and cells through to tissues, organs and intact organisms.

Specific methodologies include: in vivo and in vitro cardiovascular and pulmonary pharmacology, cancer therapeutics and neurogenerative diseases, enzyme purification, spectral analysis, immunoassay, radioligand binding, in situ hybridisation, PCR, cDNA analysis, Western analysis and immunoprecipitation, proteome mapping, receptor cloning, cell culture, single cell electrophysiology, live cell imaging, bioluminescence, immunocytochemistry of total and activated proteins and behavioural testing.

Current research interests include:
cell signalling, especially in cancer and cardiovascular disease
airway diseases
smooth muscle pharmacology
neurodegenerative diseases
applications of chemo/bioluminescence

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